The question of putative mechanisms of action continues to haunt psychopharmacology. Put simply, we know these drugs work, but we have very little idea how. We make guesses based on the ...

Understanding the mechanisms of action of antithrombotic agents is also important for defining therapeutic strategies and managing adverse effects of these medications. The mechanisms by which the ...

The project goal is to predict the Mechanism of Action (MoA) response(s) of different samples (sig_id) using various inputs such as gene expression data and cell viability data. What is the Mechanism ...

Thus, efforts to improve potency evaluation and understanding of the mechanisms of action (MoA) are under way, to improve both the safety and efficacy of MSC therapies. MSC modulation of the immune ...

This review discusses the mechanisms of antibiotic action against Gram-positive pathogens, and resistance counter-mechanisms developed by Gram-positive bacteria, with emphasis on the newer agents.

Many people wish not only to live as long as possible, but above all to do so without any health restrictions. However, with ...

This cellular effect of antithrombin is very similar to that of HRG, which has the same CLEC1A as its receptor, suggesting a completely new functional role and mechanism of action for this plasma ...

A research team at KAIST has identified the core gene expression networks regulated by key proteins that fundamentally drive phenomena such as cancer development, metastasis, tissue differentiation ...

The current research status and perspectives, focusing on the action modes and mechanisms of herbal glycans which may be sweet medicine of tomorrow, should be well investigated, which are also ...

The metabolism and particularly the decarboxylation of methyldopa were studied in hospitalized patients with uncomplicated hypertension. Both unlabeled and radioactive drugs were employed in these ...

The mechanism of action of ROR2 blockade was independent of modulation of canonical WNT signaling. YAP inhibition was required, but not sufficient, for the chondrogenic effect (4). Therefore, ...