Antibiotics are a double-edged sword—they should be as toxic as possible to pathogenic bacteria while being harmless to the cells of the human ... pathway is an essential part of the energy ...

All metabolic pathways have to be regulated and controlled to stop the build-up of an end product that isn’t needed. The cell can control a metabolic pathway by the presence or absence of a ...

The new molecules target a metabolic pathway that only occurs in bacterial cells, thus sparing human cells. The team published its results in the journal Angewandte Chemie International Edition.