Metabolism and individuality in drug response The need to understand individuality in drug response and associated benefits is a primary force behind the current industry trend toward the ...

Even well-known drugs can cause entirely unpredictable effects on metabolism, Swiss researchers have shown. Rapidly mapping ...

The NMR and Drug Metabolism Core has developed rapid and efficient approaches to investigate metabolism, metabolic stability, pharmacokinetics (PK), and chemical structure identification of small ...

Metabolism in cancer cells differs from that in normal cells, but it is only recently that opportunities to specifically target these differences to develop novel anticancer drugs are being revealed.

The application of pharmacogenetics in identifying single nucleotide polymorphisms (SNPs) in DNA sequences that cause clinically significant alterations in drug-metabolizing enzyme activities is ...

Scientists have unveiled a groundbreaking method to test how thousands of active substances influence cellular metabolism ...

The NMR and Drug Metabolism Core at Baylor College of Medicine offers tools to support the discovery, synthesis, screening, optimization, metabolism and pharmacokinetics of small molecule ligands or ...

They also revealed a new strategy to target this metabolic system with new and existing drugs. The findings are published in Cell Metabolism. "Lipids have been associated with Alzheimer's for as ...

Despite such growth, there remains a set of complex hurdles associated with drug development for rare metabolic diseases. Inborn Errors of Metabolism Drug Development 2020 is dedicated to ...

Ozempic and Wegovy do the same thing as GLP-1 would normally do for you — but to enable them to treat diabetes and obesity, ...