The NMR and Drug Metabolism Core has developed rapid and efficient approaches to investigate metabolism, metabolic stability, pharmacokinetics (PK), and chemical structure identification of small ...

Metabolism and individuality in drug response The need to understand individuality in drug response and associated benefits is a primary force behind the current industry trend toward the ...

Even well-known drugs can cause entirely unpredictable effects on metabolism, Swiss researchers have shown. Rapidly mapping ...

Researchers at the University of Basel are able to test in parallel the effects of over 1,500 active substances on cell metabolism. Their analysis also led to the discovery of previously unknown ...

Metabolism in cancer cells differs from that in normal cells, but it is only recently that opportunities to specifically target these differences to develop novel anticancer drugs are being revealed.

Scientists have unveiled a groundbreaking method to test how thousands of active substances influence cellular metabolism ...

They also revealed a new strategy to target this metabolic system with new and existing drugs. The findings are published in Cell Metabolism. "Lipids have been associated with Alzheimer's for as ...

drugs, or even food. Whole human body GEMs can also serve as an atlas for the metabolism of complex diseases. They can help map how the chemical environment of the body changes with obesity or ...

Despite such growth, there remains a set of complex hurdles associated with drug development for rare metabolic diseases. Inborn Errors of Metabolism Drug Development 2020 is dedicated to ...