In patients treated with intravenous metronidazole, using a dosage regimen of 15 mg/kg loading dose followed 6 hours later by 7.5 mg/kg every 6 hours, the average peak steady-state plasma ...

Metronidazole exerts antibacterial effects in an anaerobic environment against most obligate anaerobes. Once metronidazole enters the organism by passive diffusion and activated in the cytoplasm ...

Nitroimidazole derivatives are the drugs of choice for treatment of amoebic colitis, as they are very effective against the trophozoite form of the parasite (metronidazole 750–800 mg three times ...