On the other hand, disturbed monocyte function is associated with "immune paralysis". In this condition, the immune system's ability to fight off invaders such as viruses and bacteria is inhibited.

Illustration shows the new function of blood monocytes, namely their ability to proliferate in tissues before differentiating into macrophages, immune cells that play important roles in ...

Monocytes and macrophages are myeloid cells that have important innate immune functions. Macrophages reside in tissues and respond to infection by producing inflammatory mediators and engulfing ...

Moreover, we found that monocyte-derived TAMs function as antigen-presenting cells to regulate CTL activation and exhaustion in tumors. We also found that tumor growth induces overly activated ...