Previous attempts to humanize this antibody had come to a dead end. The scientists fed the sequence of the mouse version of this antibody into the program, choosing the most-likely-to-succeed ...

The sequence homology is over 95% ... antibodies Affinity evaluated by ELISA and SPR/BLI Before humanization, mouse antibody K D =6.38E-12M. Image Credit: Sino Biological After humanization ...

Antibodies from AlivaMab Mouse exhibit druglike biophysical properties ... The company provides the necessary expertise to produce large panels of sequence and epitopediverse, high-affinity ...

The new kits enable researchers to profile the mouse BCR repertoire ... "Deep Mining of Antibody Repertoires with Single Cell B Cell Sequencing Tools," for more details.

Both methods combine antibody-oligonucleotides with existing single-cell RNA-sequencing (scRNA-seq ... and 13 cell-surface proteins of human and mouse immune cells. They showed that CITE-seq ...

FMC63, an IgG2a mouse monoclonal antibody, targets CD19. To date, a majority of the reported CART19 trials include the anti-CD19 scFv extracted from FMC63, such as both the FDA-approved CARs ...