However, skin color, height, and nearly all other common forms of natural ... 1.2.2 Castle, Little, and the founders of mouse genetics The most significant force in early genetic work on the mouse was ...

The significance of the interspecific cross for mouse genetics cannot be understated: it was the single most important factor in the development of a whole genome linkage map based on molecular ...

A team of stem cell scientists have successfully used embryonic stem cell engineering to create a bi-paternal mouse -- a mouse with two male parents -- that lived until adulthood. Their results ...

As shown in the Timeline, large-scale mouse mutagenesis is divided into three phases. In 1997, ENU mutagenesis began with the use of forward genetics, primarily focusing on dominant phenotypes.

Making Mice is, to a large extent, the story of Clarence Cook Little and his effort to establish standardized inbred mouse lines as essential resources in the study of genetics and cancer.

The Knockout Mouse Phenotyping Program (KOMP2) sites at Baylor College of Medicine, Jackson Laboratory, and University of California, Davis, are collaborating with the International Mouse Phenotyping ...