Researchers have described the development of a novel murine model of glioblastoma established with a patient-derived xenograft (PDX) in humanized mice that harbored an almost complete human immune ...

Ogilvie's lab utilizes biologically relevant mouse xenograft models where human MB cells are implanted into the cerebellum ... TurboID and digital spatial profiling of brain tumor tissue with ...

Furthermore, in vivo experiments using mouse xenograft models confirmed that ING5 overexpression inhibited tumor growth and metastasis, effects that were reversed by the Y163F mutation.

In MM mouse xenograft models, OPN-6602 showed 71% tumor suppression as a single agent, and 100% tumor regression when combined with dexamethasone, pomalidomide or mezigdomide with a sustained ...

Glucocorticoids can either suppress or promote tumor progression ... The in vivo experiments involved orthotopic xenografts, in which human and mouse glioblastoma cells were injected directly ...