Department of Chemistry, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, United States Carl R. Woese Institute for Genomic Biology, University of Illinois at Urbana-Champaign, ...

Researchers have described the development of a novel murine model of glioblastoma established with a patient-derived xenograft (PDX) in humanized mice that harbored an almost complete human immune ...

Isotype-matched human immunoglobulins served as controls. Finally, the cells were counted with the FACS scanner. Xenograft tumor studies were conducted utilizing the 6-week-old male BALB/c nude mice ...

Importantly, the cytotoxic activity of neutrophils driven by therapeutic EGFR or HER2 antibodies in vitro was increased by blocking the sialic acid/Siglec interaction, either by reducing tumor cell ...

Furthermore, in vivo experiments using mouse xenograft models confirmed that ING5 overexpression inhibited tumor growth and metastasis, effects that were reversed by the Y163F mutation.

Ogilvie's lab utilizes biologically relevant mouse xenograft models where human MB cells are implanted into the cerebellum ... TurboID and digital spatial profiling of brain tumor tissue with ...