Multiple myeloma is one of the most common forms of cancer of the immune cells in the bone marrow. It is considered incurable. Even when patients respond to treatment at first, the cancer comes back.

What causes multiple myeloma? No one knows exactly, but certain things can raise your chances of getting this blood cancer. You’re more likely to get multiple myeloma if a family member has it ...

Multiple myeloma is a rare type of cancer. It starts with the uncontrolled production of plasma cells. These are a type of white blood cell in the bone marrow. Healthy plasma cells make antibodies ...

So they know they have cancer, but they really don't know what to expect. So what you want to determine is, how serious is the multiple myeloma? How extensive is it? How is it affecting other organs?

Here, we report on the anti-tumor activity of a CAR T-cell possessing two complete and independent CAR receptors against the multiple myeloma antigens BCMA and CS1. We determined that the ...

More information: Raphael Lutz et al, Bone marrow breakout lesions act as key sites for tumor-immune cell diversification in multiple myeloma, Science Immunology (2025). DOI: 10.1126/sciimmunol ...

The findings showcase a promising approach to bone healing and tumor control. The team tackled a critical challenge in treating multiple myeloma -- a blood cancer where malignant plasma cells ...

The team tackled a critical challenge in treating multiple myeloma-a blood cancer where malignant plasma cells accumulate in bone marrow, leading to debilitating bone lesions in 80% of patients ...

"This innovation addresses a significant unmet need in multiple myeloma treatment by combining structural bone repair with targeted tumor control. We are eager to move towards clinical testing to ...

Allogeneic transplants also can treat multiple myeloma. When you have an allogeneic stem cell transplant, stem cells are harvested (collected) from a donor. For either type of transplant, you first ...