the possible correlation between virus infections and multiple sclerosis (MS) pathogenesis is based on two main hypotheses: the 'prevalence hypothesis' and the 'poliomyelitis hypothesis'.

This article reviews MS pathogenesis and rationale for maintaining neurological reserve. MS has classically been thought of as a white matter disease. 13 Although it is now known that GM plays an ...

From this brief review regarding the possible relationship between infectious agents and MS, it appears clear that this phenomenon cannot be viewed in the simplistic way of the dogma 'a specific ...