The importance of TGF-β family proteins in muscle cell differentiation is well illustrated by the effects of myostatin/growth development factor (GDF)-8, a TGF-β family member that is first ...

Innovative muscle patches derived from stem cells demonstrate efficacy in heart repair, improving function in primates and a ...

Within multicellular organisms, tissues are organized communities of cells that work together to carry out a specific function. The exact role of a tissue in an organism depends on what types of ...

Our longterm goals are to understand the mechanisms regulating the growth, differentiation and self-renewal of skeletal muscle satellite cells for eventual use in cell-based gene therapy approaches.

C2C12 cells, a mouse myoblast cell line ... was used to measure the expression levels of muscle differentiation-related genes. Additionally, immunostaining against myosin-heavy chain provided ...

The differentiation and functional properties of smooth muscle cells depend on the cellular environment, and any disturbance of this, such as endothelial damage, inflammation or lipid retention will ...