Exogenous expression of aurora A led to an accumulation of ubiquitylated MYCN, indicating that stabilization is effected at a post-ubiquitylation step. However, transfection of ubiquitin in which ...

However, dysregulation of MYC, such as amplification of MYCN, is associated with tumorigenesis, especially for neuroblastoma. MDM2, on the other hand, is one of the most frequently studied ...