Researchers find that certain antioxidant enzymes, called selenoproteins, significantly contribute to fighting cell aging. The team used a gene knockout mouse model to help them study the effects of ...

3 Lu focused on granulocytes and B cells, which are the most abundant myeloid and lymphoid immune cells ... Then they mapped single-cell lineage output to gene expression against a cDNA library to ...

Mixed lineage leukemia (MLL)-fusion proteins can induce acute myeloid leukemias (AMLs) from either hematopoietic stem cells (HSCs) or granulocyte–macrophage progenitors (GMPs), but it remains ...

This is the process through which these cells differentiate towards the myeloid lineage, ending up resembling naïve microglia. As part of their recent study, the researchers set out to ...

Dana-Farber Cancer Institute researchers have identified factors that determine whether donor lymphocyte infusion (DLI), a ...

This platform has revealed an essential role for myeloid lineage cells—particularly neutrophils—in excluding tumor-reactive lymphocytes from the malignant portion of tumors. The current focus of the ...

A research team made a pivotal discovery in the field of cancer immunotherapy. The team identified a specific population of immune cells that play a critical role in successful treatment of relapsed ...