Upon initial activation by their cognate antigen, naïve CD8 + T cells start to proliferate and differentiate into short-lived effector and long-lived memory precursor cells. How a single ...

Pathogen-fighting immune cells called tissue-resident memory CD8 T cells (TRM cells) go through a surprising transformation -- and relocation -- as they fight infections in the small intestine.

The human immune system is like an army of specialized soldiers (immune cells) each with a unique role to play in fighting ...

Researchers identify a pathogenic subset of CD8+ memory T-cells that promote airway tissue inflammation and recurrent ...

At the same time, they discovered favorable disease-fighting capabilities such as robust expansion and resistance to exhaustion of 'naïve' cells ... then in human cells. T cells were taken ...