Unlike CAR-T cells, NK cells don’t need genetic modification to recognize a specific threat — they act broadly without ...

Unmodified natural killer (NK) cells work differently from the T-cells upon which CAR-T therapies are based – NKs are usually involved in killing cells that are infected with viruses, whereas T ...

Like CAR-T cell therapy, in which immune cells called ... this new approach engineers a different type of immune cell called a natural killer (NK) cell. For the new therapy, these cells are ...

Moreover, patients who had undergone prior CD19-directed CAR T-cell therapy had a complete ... [induced pluripotent stem cell]-derived CAR [natural killer] cells are a highly promising approach ...

Talimogene laherparepvec (T-VEC) demonstrates efficacy in cutaneous BCC, enhancing resectability and altering immune cell ...

An investigational induced pluripotent stem cell-derived CAR natural killer cell therapy was well ... who had received previous autologous CAR T-cell therapy, an area of continued unmet need ...