Researchers found that electric fields inside embryos guide migrating cells. The enzyme Vsp1 helps cells sense and respond to ...

We have described the clinical manifestations of isotretinoin (ISO) neuroembryopathy (J Ped, 105, 595, 1984) and with others have suggested that disturbances in neural crest development may ...

As an embryo grows, there is a continuous stream of communication between cells to form tissues and organs. Cells need to read numerous cues from their environment, and these may be chemical or ...

Researchers have identified endogenous electric fields in developing embryos that guide the migration of neural crest cells, ...

Specific functional, electric firing properties of those neurons are shown by electrophysiology. Directing neural crest and sensory placode lineages Multipotent neural crest (NC) precursor cells have ...

Building and shaping an embryo requires the concerted effort of numerous signals and molecular interactions during development. One essential aspect of this process is collective cell migration, where ...

The ZIC2 gene drives the migration of neural crest cells (in green) during early embryonic stages, a process essential for forming the vertebrate nervous system. Credit: The American Journal of ...

Additionally, the team used animal models, including mice and chicken embryos, to observe in vivo how ZIC2 regulates the migration of neural crest cells and to examine the defects associated with ...