Morphological profiling allows accurate identification of cell types in dense iPSC-derived cultures, allowing its use for quality control and differentiation monitoring.
Sphere of Influence. In iAssembloids, microglia (red) form projections (white arrows), while astrocytes (green) assume star shapes typically found in the brain. [Courtesy of Kampmann et al., 2025.] ...
The microglia, a group of cells which are nicknamed the ‘housekeepers’ of the brain play an integral role in maintaining neural health. These tiny but mighty cells are the brain’s first ...
The Xu laboratory works on developing human stem cell models to study the underlying mechanisms of human neurological disorders, such as Alzheimer's disease, and apply these models for drug screening.
Immune cells in the brain called microglia can partially break down large amyloid plaques characteristic of Alzheimer's disease by latching on to them, forming a sort of external stomach and ...
Not only is hippocampal neurogenesis ablated, but the remaining neural precursors adopt glial fates and transplants of non-irradiated neural precursor cells ... status of microglia within the ...