Researchers from the Epigenetics and Immune Disease Laboratory at the Josep Carreras Leukaemia Research Institute in ...
The incorporation of blood-brain barrier-like structures and immune cells, such as microglia, into these organoids allows researchers to investigate how these components influence neural ...
The microglia, a group of cells which are nicknamed the ‘housekeepers’ of the brain play an integral role in maintaining ...
Microglia are the brain's immune cells known to play a vital role in maintaining neural function and responding to potential threats. However, when the brain is subjected to hyperosmotic stress ...
Microglia, the brain's immune cells, exhibit altered gene expression and a weakened immune response as they age, potentially contributing to neurological disorders like Alzheimer's and Parkinson's.
Sphere of Influence. In iAssembloids, microglia (red) form projections (white arrows), while astrocytes (green) assume star shapes typically found in the brain. [Courtesy of Kampmann et al., 2025.] ...
Morphological profiling allows accurate identification of cell types in dense iPSC-derived cultures, allowing its use for quality control and differentiation monitoring.
A research group from Nagoya City University has elucidated the significance of birth in the maintenance of neural stem cells ...
Their findings indicate these cells play a key role in initiating ... protein 18 kDa (TSPO), a marker of microglial activation (image at right), while FDG-PET revealed reduced glucose metabolism, a ...
Researchers investigate the sex-dependent microglial response to a colony-stimulating factor 1 receptor (CSF1R) inhibitor.