A non-opioid painkiller from Vertex Pharmaceuticals could become a blockbuster, but questions remain on whether it will prove ...

Objective: To assess the efficacy, safety and impact on quality of life of tramadol in the treatment of neuropathic pain in patients with cancer. Methods: Patients with similar characteristics ...

The heterogeneous nature of the mechanisms underlying neuropathic pain complicates the selection of appropriate treatments for individual patients. Although systematic reviews have outlined the ...