These sacs spill their contents into the synapse, where the neurotransmitters then move across the gap toward the neighboring cells. These cells contain receptors where the neurotransmitters can ...

Dopamine’s effects in the brain are mediated by postsynaptic D1 and D2 receptors. Adenosine A1 and A2A receptors are uniquely positioned to counteract the excessive stimulation of dopamine receptors ...

They observed hundreds of presynaptic terminals simultaneously releasing the neurotransmitter ... design FFNs to target other transporters and receptors. In all likelihood, FFN511 will soon ...

Serotonin is primarily synthesized by neurons in the dorsal Raphe nucleus (DRN) in the midbrain. Serotonin neurons in the DRN project to numerous brain regions, including the arcuate of the ...

Recreational drugs can affect neurotransmitters in the reward pathway ... Agonists stimulate specific receptors which decreases the number and sensitivity of the receptors. As the sensitivity ...

“The end game is trying to relate [dopamine signaling] back to schizophrenia and other disorders with working memory impairment,” study coauthor Joshua Roffman of MGH and Harvard University told The ...

The modulatory neurotransmitters activate G protein-coupled receptors, which share signal transduction systems in cells. In addition to regulating key physiological functions, these systems are ...

Their findings, published in Nature Neuroscience, suggest that different aspects of reward-related behavior are supported by two distinct dopamine receptors, namely D3 and D1. "The previous ...

Specific protein receptors in the brain play a vital role in how neurons slow down or stop firing, making them targets for ...