reflecting the sensitization of central nociceptive neurons to mechanically evoked input. Successful neuropathic pain management requires the definition of precise sensory profiles. The diagnostic ...

Treatment with XG005 resulted in statistically significant and clinically meaningful reduction in post-surgical pain ...

We received a question this month asking how to help with nerve pain. It is from someone who was involved in a car accident in early 2023 and damaged his lower vertebrae, fractured his right hip ...

In a rat model of neuropathic pain, mild cooling of the skin or peripheral ... II/III metabotropic glutamate receptors (inhibitors of nociceptive responses). By contrast, results were obtained ...

There are two types of pain associated with HS: nociceptive (localized) and neuropathic (nerve) pain. HS pain can affect a person's quality of life, affecting their work, intimacy, and mental health.

A trial with XG005 met it's primary and secondary endpoints, demonstrating a statistically significant reduction in ...

XG005 is a novel molecule targeting two distinct pain pathways: an anti-nociceptive and an anti-neuropathic. It is potentially first-in-class oral treatment that is in parallel development for ...

Often when we think of pain it is the nociceptive kind, the acute pain that comes with injury or tissue damage caused by a specific event. Neuropathic pain, on the other hand, tends to be chronic ...