Multicellular organisms must evolve mechanisms to suppress cancer formation prior to reproduction, and we propose that the organizational structure of normal epithelium is one such strategy.
Normal mouse stomach epithelium (above) versus epithelium with p57 overexpression (below) at day 3 post-injury with high-dose tamoxifen (HDT). The epithelium is stained for chief cells (magenta ...
The EASI method is applicable to most normal, preneoplastic and malignant ... The inherent property of desmosome-rich epithelial cells to separate from surrounding stromal tissues as tightly ...
Barrett's esophagus is an acquired metaplastic abnormality in which the normal stratified squamous epithelium lining of the esophagus is replaced by an intestinal-like columnar epithelium.