Additionally, pathologists use IHC to predict whether tumor cells will respond to certain treatments ... Trusted ways to accomplish this are blocking the tissue with either 5-10 percent normal goat ...

From histopathology to multiplex immunohistochemistry and spatial transcriptomics, learn how to obtain the appropriate profiling depth to match cancer classification needs. Histological analysis of ...

The following is a summary of “Clinical significance and pro-oncogenic function of DBF4 in clear cell renal cell carcinoma,” published in the January 2025 issue of Urology by Chen et al. Clear cell ...

[67] PCR assays can then be developed to detect rearrangements in normal blood ... over the next 3 years. IHC: Immunohistochemistry; NSCLC: Non-small-cell lung cancer. Adapted with permission ...

All positive (IHC 3+) and doubtful (IHC 2+) cases were screened by fl uorescence in situ hybridization (FISH). Patients with HER2 gene amplification, normal ... or elevated cancer antigen 125 ...

The HER2-low and HER2-ultralow breast cancer subtype designations have led to a changed landscape in HER2-directed therapies, as well as a desire for more sensitive assays that may better quantify ...

This reflects tumor cells' ability to grow and divide even in the absence of growth factors. Finally, transformed cells overcome the restriction of limited rounds of replication seen in normal ...

We’ll also discuss the advances in multiplex IHC using Opal and rabbit primary antibodies developed by CST to reliably stain for 6 markers in a mouse model of breast cancer and how Akoya Bioscience’s ...