TNFRSF11A encodes the receptor activator of NFκB (RANK), which is critical for normal osteoclast formation; genetic variants in this gene result in familial expansile osteolysis, a Paget-disease ...
Researchers at Hospital for Special Surgery (HSS) have pinpointed a cellular target that could enhance the way osteoporosis and other metabolic bone diseases are diagnosed and treated. The findings, ...
Hayata and Yasuhiro Arasaki from TUS tackled these knowledge gaps. Motivated by the intricate and complex process of osteoclast differentiation, they sought to more thoroughly understand how the ...