Discovery of Type R capillaries: key player in bone remodeling, ageing, osteoporosis treatment and bone regeneration.

Bones are the living tissue on which the human skeleton is constructed and play a key role in enabling physical movements.

Osteoclasts develop from the development of macrophages or monocytes, two types of immune cells. Suppressing osteoclast differentiation could thus be used as a therapeutic technique to prevent ...

The key components of AP1, the Fos and Jun proteins, have essential roles in bone development, because these proteins influence the activity of all bone cells, including chondrocytes, osteoblasts, and ...

This is an interesting work on mental stress on bone health and osteoporosis, and the authors offer solid evidence of decreased bone mass mediated by miR-335-3p/Fos signaling in osteoclasts that are ...

Osteoclasts are a type of cell that plays a crucial role in bone maintenance. These cells absorb and break down old or broken bones , letting the body reuse key elements such as calcium and ...

Using mice, Ishii captured footage of osteoclasts breaking down bone tissue for the first time in the world. 06:00 The blue areas are bone, and the red parts resembling amoebas on the bone's ...

Here, we investigated the role of autophagy during joint destruction in arthritis. Methods Autophagy in osteoclasts was analysed in vitro and ex vivo by transmission electron microscopy, Western ...

Little information is available about the early post-condensation period, during which avascular soft condensation turns into vascularized bone, and all three major bone cell types, osteoblasts, ...