Beyond a threshold (which is lowered when autophagy is inhibited), such stress causes apoptosis. Several proteins that have an essential role in autophagy have a direct or indirect impact on the ...
Moreover, free radicals probably play a role in the body s tumor suppression by mediating programmed cell death (apoptosis). Immune-relevant cells also use the reactive ... They also influence signal ...
By around 2000, apoptosis had become the prominent mode ... Mechanistic studies of intrinsic hepatotoxins have revealed oxidative stress and mitochondrial dysfunction as key contributors to ...
Dihydromyricetin (Dih), a naturally occurring flavonoid, has been identified to exert a protective effect against ischemia/reperfusion injury. However, the detailed mechanisms remain unclear. Here we ...