pharmaphorum19d
Cost control urged for new PCSK9 cholesterol drugs
Pharmacy benefits manager CVS Health has warned that the new PCSK9 inhibitor class of cholesterol-lowering drugs poses an unprecedented challenge to the US healthcare system. In a blog post ...
The Globe and Mail1mon
PCSK9 Inhibitors Treatment Market 2034: Clinical Trials, Medication, Pipeline Therapies, EMA, PDMA, FDA Approvals and Companies by DelveInsight
PCSK9 Inhibitors Companies are Sirnaomics, Vaxxinity, Verve Therapeutics, Xinlitai Biotechnology, Novo Nordisk, AstraZeneca, Akeso Biopharma, Amgen, Jiangsu Hengrui ...
pharmaphorum8mon
AstraZeneca throws its hat into the oral PCSK9 ring
AstraZeneca has reported the first clinical data with its oral PCSK9 inhibitor AZD0780, which it hopes could offer an alternative to current injectable drugs used to lower cholesterol. The new ...
Knowridge5d
Research shows surprising harmful effects of cholesterol-lowering drugs
Both types are effective at managing cholesterol, but researchers have uncovered some surprising side effects. Weight Gain: ...
The Scientist5y
Novartis’s $9.7 Billion Purchase Includes Novel PCSK9 Inhibitor
In the past few years, pharmaceutical companies have produced a class of drugs that lower cholesterol by inhibiting a protein called PCSK9 in a new attempt to reduce the risk of heart disease, the ...
MedCity News5y
PCSK9 inhibitors
The progress in artificial intelligence (AI) is reshaping patient care, across various dimensions, from facilitating faster discharge to curating treatment plans and suggesting lifestyle changes ...
Medscape2d
Treatment of Homozygous Familial Hypercholesterolemia
Inhibitors of LDL synthesis, lomitapide and mipomersen, are new therapeutic options. PCSK9 inhibitors are being evaluated in HoFH and seem to be effective if there is residual receptor activity.
WebMD13d
What Happens When Statins Don’t Work?
so they don’t have that same effect of causing liver damage. PCSK9 inhibitors are a new class of medications that may be available to patients to help reduce their cholesterol. By inhibiting a ...
Hosted on MSN20d
For Your Patients: Medication to Manage Cholesterol
These drugs reduce the cholesterol your body makes ... get rid of cholesterol in the body and typically reduce LDL levels by 15-30% PCSK9 inhibitors -- alirocumab (Praluent), evolocumab (Repatha ...
FierceBiotech22d
Scribe slims down workforce as it readies cardiometabolic genetic meds for clinic
The firm’s epigenetic gene silencer STX1150 reduced secretion of the enzyme PCSK9, lowering the animals’ levels of low-density lipoprotein cholesterol, Scribe said in a Nov. 25 release.
Medscape4d
Treatment of Homozygous Familial Hypercholesterolemia
HDL is reduced. PCSK9, which reduces LDL receptor recycling, is increased. E3-ubiquitin ligase inducible degrader of the LDL receptor has a similar function, but its role in familial ...