Recent evidence shows that tumor-associated macrophages also express PD-1, suggesting that PD-1/PD-L1 therapies may also have a direct effect on macrophages 1. Combinatorial blockade of PD-L1 and ...
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Dual-target drug may lead to new treatment approach for breast cancer patientsResearchers, led by the University of Melbourne's Professor Laura Mackay, a Laboratory Head and Immunology Theme Leader at ...
而癌细胞表面表达的PD-L1，当然是制约抗肿瘤免疫应答的敌人，所以帮助PD-L1存在的“敌人的朋友”，当然也要打击才行。 近日，西安交通大学李磊 ...
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Macrophages, not T cells, may hold key to predicting which melanoma patients are more likely to respond to immunotherapyInstead, they found that changes in the macrophages correlated to which patients ... has monitored amounts of protein indicators such as PD-L1 and at the genes involved in T cells to assess ...
Aligos Therapeutics Inc. has disclosed programmed cell death 1 (PDCD1; PD-1; CD279) and/or PD-1 ligand 1 (PD-L1; CD274) and/or PD-1/PD-L1 interaction inhibitors reported to be useful for the treatment ...
Focus is on role of LRRK2 in PD-related inflammatory processes Does LRRK2 inhibition in the periphery block α-syn driven pro-inflammation and neurodegeneration? Do macrophages from LRRK2 mutation ...
New research highlights the potential of the novel diagnostic tool iFRET to determine immunotherapy outcomes in stage 2 ...
In the ALEXANDRA/IMpassion030 trial, Tecentriq (atezolizumab) added to postoperative chemotherapy was not found to improve ...
近日，来自复旦大学药学院陆伟教授、上海交通大学医学院肖泽宇教授该研究在 Nature Communications发表了题为 “CD133+PD-L1+ cancer cells confer resistance to adoptively transferred engineered macrophage-based therapy in ...
Recent evidence shows that tumor-associated macrophages also express PD-1, and suggests that PD-1/PD-L1 therapies may have a direct effect on macrophages too. Combinatorial blockade of PD-L1 and ...
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