Haploinsufficiency of the Pten tumor suppressor gene promotes prostate cancer progression ... Pathobiology of Autochthonous Prostate Cancer in a Pre-clinical Transgenic Mouse Model. The Prostate 55: ...

This is a useful study that seeks to address the role of the TET family of DNA demethylation enzymes in pancreatic beta cell senescence in the context of type 2 diabetes (T2DM). Although the concepts ...

The findings, which were translated from a preclinical animal model into a human study ... improves insulin sensitivity by suppressing PTEN, a gene that prior studies have linked to obesity ...