The understanding of the pathophysiology of atherosclerosis and related vascular diseases has changed over the last decade, providing new perspectives for preventive and therapeutic strategies.
Here I discuss recent advances in the study of endoplasmic reticulum stress as one mechanism that links immune response with nutrient sensing in the pathogenesis of atherosclerosis and its ...
These findings indicate AGE–RAGE interaction is involved in the pathogenesis of accelerated atherosclerosis in diabetes, and identify RAGE as a new target for therapeutic intervention in ...
Circ Res. 2018;1a] The term “athero” means porridge and “sclerosis” means scarring, which is how atherosclerosis was first described on autopsy. The pathogenesis of atherosclerosis is ...
These observations have led to the conclusion that AAAs are a consequence of advanced atherosclerosis. This review explores current theories regarding the pathogenesis of AAA and their ...
Dr. Bacha’s laboratory at the Children’s Nutrition research Center (CNRC) investigates the risk factors and mechanisms underlying the pathogenesis of the metabolic complications related to childhood ...