Apoptosis, a process important for clearing damaged or infected cells, is the induction of cell suicide and can be triggered by either intrinsic cues or activation of the relevant pathways by ...

Selective modulation of the apoptotic machinery has been the goal of oncology developers for more than two decades. The field continues to face special challenges. Many of the targets are ...

While the team's findings begin to explain a long-unanswered question about one of the primary regulators of apoptosis, they raise new ones, as well. "I think that this main pathway of apoptosis ...

Research reveals IGFBP6's role in suppressing vascular inflammation and atherosclerosis, suggesting it as a novel target for ...

Today, methamphetamine (METH) is being used by adolescents and young adults. Our previous research demonstrated that intrauterine exposure to METH induces apoptosis in testicles and seminiferous tubes ...

The main goal of our laboratory is the identification and characterization of signal transduction pathways that cause the dysregulation of growth and inhibition of apoptosis that characterize advanced ...

Dihydromyricetin (Dih), a naturally occurring flavonoid, has been identified to exert a protective effect against ischemia/reperfusion injury. However, the detailed mechanisms remain unclear. Here we ...