polycystic ovary syndrome has much variation in its clinical expression based on ancestry. Ethnic differences of the phenotype are closely linked to its complex pathophysiology. This paper reviews ...

Over the next 5–10 years we will see published studies from GWAS in PCOS that will provide new insights into the pathogenesis of this complex condition. It is likely that hitherto unexpected ...

Immunological factors, such as chronic low-grade inflammation characterized by a rise in CRP levels, IL-6, and TNF-α, are involved in PCOS pathogenesis. Chronic inflammation and oxidative stress ...