The mitochondrial oxidative phosphorylation (OXPHOS ... recent years have seen the description of the underlying genetic mutations in mitochondrial and nuclear genes. Advances in this arena ...

This manuscript describes the identification and characterization of 12 specific phosphomimetic mutations in the recombinant full-length human tau protein that trigger tau to form fibrils. This ...

Figure 4: The molecular mechanism by which phosphorylation inhibits GSK3. Figure 5: Several signalling pathways induce the inhibition of GSK3 by phosphorylating the same serine residue near the ...

One of the underlying mechanisms of ASD symptoms by Dyrk1a mutation, which was discovered within this study, is impaired phosphorylation levels of mTOR (mammalian target of rapamycin). To find the ...

This study uncovered one of the mechanisms behind ASD symptoms associated with Dyrk1a mutations: disrupted phosphorylation of mTOR (mammalian target of rapamycin). Sign up for Chip Chick's ...

One of the underlying mechanisms of ASD symptoms by Dyrk1a mutation discovered within this study is impaired phosphorylation levels of mTOR (mammalian target of rapamycin). To find the specific ...