Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare and aggressive form of blood cancer that primarily affects older adults. It is characterized by the proliferation of precursors of ...
The SnoopVacs vaccine molecule consists of antigens linked to a species-specific generic section, which directs specific antigens to plasmacytoid dendritic cells (pDCs) and B cells through ...
A research team at the Medical University of Vienna led by Maria Sibilia has investigated a new combination therapy against cancer. This therapy employs systemic administration of the tissue hormone ...
is revealed to function as an intracellular DNA-binding protein that controls TLR9 activation in plasmacytoid dendritic cells (pDCs). This discovery provides insights into the functional ...
Various cell types contribute to dysregulation of immune responses in MDS. Dendritic cells (DCs) are important regulators of immunity. However, the role of DCs in MDS has yet to be elucidated.