50 is not only a potent inhibitor of platelet aggregation, but also interferes with processes leading to hypertension, atherogenesis and cardiac dysfunction. In a randomized study, diclofenac ...

This medication is a platelet aggregation inhibitor, prescribed for thrombotic cardiovascular (CV) events (life-threatening problems with the heart and blood vessels), in patients who had heart ...

Monthly measurements of platelet aggregation revealed that AZD6140 was a significantly more potent inhibitor of aggregation (at both doses) than was clopidogrel and that the effects of AZD6140 ...

When given as an intravenous bolus, immediate and full platelet inhibition of ADP-induced platelet aggregation was observed. The clinical efficacy and safety of elinogrel will be further evaluated ...

Additionally, intrahepatic platelet aggregation was detected and quantified ... Furthermore, other studies indicated that platelets can secrete hepatic growth factor to inhibit the activation of ...

1 Rutgers University-New Jersey Medical School, Department of Neurosurgery, Newark, New Jersey, United States 2 Yale University School of Medicine, Department of Neurosurgery, New Haven, Connecticut, ...

Aspirin inhibits platelet aggregation by irreversible inhibition of platelet cyclooxygenase and thus inhibits the generation of thromboxane A2, a powerful inducer of platelet aggregation and ...

dadlnet.dk Objective To evaluate the effect of proton pump inhibitors (PPIs) on the platelet response to aspirin in patients ... enteric coated aspirin 75 mg/day and received no other antithrombotic ...

rcsi.ie BACKGROUND Selective inhibitors of cyclooxygenase (COX)-2 may provoke less gastric damage and platelet inhibition than conventional non-steroidal anti-inflammatory drugs. AIMS We compared the ...

that competitively inhibit HMG-CoA and reduce cholesterol biosynthesis. Aspirin inhibits platelet activation and aggregation for the lifetime of the platelet by irreversibly inhibiting ...

One of the open questions is whether a subgroup of APS-patients could be treated with platelet-aggregation inhibitors like clopidogrel, instead of treatment with vitamin K antagonists (VKA) with a ...