DNA polymerase (DNAP) is a type of enzyme that is responsible for forming new copies of DNA, in the form of nucleic acid molecules. Nucleic acids are polymers, which are large molecules made up of ...

1| Combine the following components of the master mix on ice and mix thoroughly: 10× KLA reaction buffer (pH 9.2): 500 mM Tris base, 160 mM (NH 4) 2 SO 4, 25 mM MgCl 2, 1% Tween 20. Note, the pH ...

Biology lectures teach students that when a cell’s replication machinery comes together, DNA polymerase takes off down the double-helix like a car on a highway ...

But the team wanted to improve it even further. Using machine learning, they analyzed amino acid sequences to identify mutations that enhanced the polymerase’s binding to its template strand. Then, ...

For a gene to be switched on, it must be acted upon by an enzyme called RNA polymerase. This is a molecular machine which can read DNA and create ... Northwestern Medicine investigators have ...

Northwestern Medicine investigators have discovered a novel mechanism that recognizes and eliminates "bad" transcriptional elongation enzymes during ... elongation by RNA polymerase II (Pol ...

Researchers at Fred Hutch and MD Anderson discovered RNA Polymerase II on histone genes as a biomarker for cancer ...

The new technology – Cleavage Under Targeted Accessible Chromatin (CUTAC) – focuses on small, fragmented DNA non-coding ...

As the incidence of genetic disorders increases, there is a corresponding rise in the demand for molecular biology enzymes, kits, and reagents essential for conducting tests. These tools are vital for ...

TriLink BioTechnologies (TriLink®), a Maravai® LifeSciences company (NASDAQ: MRVI) and global provider of life science reagents and services, has partnered with, ...