For example, one may imagine that irreversible inhibitors of the T. cruzi protease cruzaine would show severe side effects because they also target host cysteine proteases. However, these ...
Investigators at The Scripps Research Institute and Rensselaer Polytechnic Institute have designed novel covalent inhibitors of SARS-CoV-2 papain-like protease (PLpro) and assessed their drug ...
For example, the nucleotide triplet WMC is translated ... from 'untreated' individuals (those who have not received a protease inhibitor, but may have received an RT inhibitor); non-subtype ...