Researchers have discovered how a particular protein affects the growth and spread of colon cancer in humans. The study not ...

Mitogen-Activated Protein Kinase (MAPK) signaling pathways play a crucial role in various cellular processes, including growth, differentiation, and response to stress. These pathways are ...

Researchers discovered that ALPK2, a heart-specific enzyme, may protect against HFpEF by activating TPM1 in heart muscle ...

Figure 1: The signalling pathway by which insulin inhibits GSK3 ... (IGF1, insulin-like growth factor 1; MAPKAP-K1, mitogen-activated protein kinase (MAPK)-activated protein kinase 1; PDK1 ...

"Rasopathies are a group of rare genetic disorders that are caused by mutations in genes that regulate the Ras/mitogen-activated protein kinase (MAPK) signaling pathway." "Given the rarity of this ...

The pig cardiomyocyte cells also showed upregulation of three signaling pathways — the Mitogen-Activated Protein Kinase pathway, the HIPPO/YAP pathway and the Transforming Growth Factor Β pathway.

A thorough examination of modern drugs that target particular receptors and metabolic pathways for glucose and fat metabolism is presented. Recent research has revealed innovative targets and ...

Plant pests such as bacteria and fungi lead to significant yield losses in agriculture. In order to develop new strategies ...

PRESS RELEASEAB SCIENCE PROVIDES AN UPDATE ON ITS MASITINIB PLATFORMParis, January 29, 2025, 7pm CETAB Science SA (Euronext - FR0010557264 - AB) ...

In cancer-associated cachexia, elevated TNF-α and IL-6 exacerbate muscle and fat loss by regulating multiple metabolic signaling pathways, which could be ameliorated by Z526's suppression of NF-κB ...