In this diagram of G-protein-coupled receptor activation, the alpha, beta, and gamma subunits are shown with distinct relationships to the plasma membrane. After exchange of GDP with GTP on the ...

A plasma membrane is permeable to specific molecules that a cell needs. Transport proteins in the cell membrane allow for selective passage of specific molecules from the external environment.

We are also actively investigating the regulation of Syk tyrosine kinase binding to membrane immune receptors and other signaling proteins. Syk recognizes doubly phosphorylated regions of the receptor ...

An enzyme that helps clear damaged mitochondria can act as a molecular switch and potentially prevent neurons from dying.

A new study highlighting the importance of a large protein complex called the exocyst in cell growth, division and communication reveals new functions and mechanisms that are essential to how ...