Protein phosphorylation is a covalent post-translational modification event that is essential for regulation and maintenance of most biological processes in eukaryotes 1. Conventionally ...
The most common techniques for detecting and quantifying protein phosphorylation today are immunoprecipitation and western blotting. Both techniques require large numbers of the cells of interest ...
Acute myeloid leukaemia (AML) is mainly characterized by an increase in the number of myeloid cells in the bone marrow and a decrease in mature cells, accounting for 28% of leukaemia cases, with a ...
Phosphorylation is involved in a wide range ... which are composed entirely of engineered protein parts, would perform with a similar speed and efficiency as natural signaling pathways found ...
Additionally, we employ quantitative mass spectrometry -based proteomics on assessing the protein abundance changes, as well as phosphorylation status of the tissues/cells. Furthermore, combining the ...