Protein phosphorylation is a covalent post-translational modification event that is essential for regulation and maintenance of most biological processes in eukaryotes 1. Conventionally ...

Researchers discovered that ALPK2, a heart-specific enzyme, may protect against HFpEF by activating TPM1 in heart muscle ...

What is ALPK2, and how can it help treat heart failure? Researchers have found that this heart-specific enzyme may prevent ...

Researchers from the Nagoya University Graduate School of Medicine identified an enzyme, alpha-kinase 2 (ALPK2) that is ...

Cell signalling pathways control plant growth, development, and responses to environmental perturbations. Protein phosphorylation is a reversible post-translation modification that is critical to ...

Cdk1-Cyclin B2 complexes are present under an inactive state due to Cdk1 phosphorylation. Progesterone activates the mPRb receptor, GPR185 is inactivated, the exocytosis and endocytosis pathways are ...

Using time-resolved proteomic analyses, the authors provide insights into changes in protein levels and phosphorylation states to an unprecedented depth, quality, and quantitative detail. The key ...

Phosphorylation is involved in a wide range ... which are composed entirely of engineered protein parts, would perform with a similar speed and efficiency as natural signaling pathways found ...

Northwestern Medicine scientists have uncovered new details explaining how poxviruses manipulate host cells to enhance their ...