Phosphorylation can either activate a protein (orange) or inactivate it (green). Kinase is an enzyme that phosphorylates proteins. Phosphatase is an enzyme that dephosphorylates proteins ...

Recent research has observed that chemical modifications called phosphorylation of proteins ... have discovered that protein kinase A (PKA) promotes wakefulness, while protein phosphatase 1 ...

Often, ligands are made of proteins, like their receptors ... binding in the extracellular domain to the kinase domain, and it ultimately leads to phosphorylation of tyrosines on the C-terminal ...

Like all cancers, bladder cancer develops when abnormal cells start to multiply out of control. But what if we could put a ...

HSV-1 is a common virus. During infection, its DNA incorporates into host chromosomes, where it lies dormant. An estimated two-thirds of adults worldwide carry these latent HSV-1 genes. Previous work ...

Kinases are enzymes that modify other proteins by adding phosphate groups to them, a process known as phosphorylation ...

A study study has uncovered the complex role of abscisic acid (ABA) in regulating chlorophyll accumulation in apple plants.

Prothena Biosciences Ltd. and Vanderbilt University have jointly discovered dual specificity tyrosine-phosphorylation-regulated kinase 1A (DYRK1A) inhibitors reported to be useful for the treatment of ...

In a paper published in Science Bulletin, a Chinese team of scientists reported a comprehensive proteogenomic analysis of 101 Chinese AML patients, including proteomic and phosphoproteomic analyses ...

The addition of Truqap to standard-of-care therapy improved radiographic progression-free survival in patients with ...