Evolution has been fine-tuning life at the molecular level for billions of years. Proteins, the fundamental building blocks of life, have evolved through this process to perform various biological ...

The tiny protein known as transthyretin can cause big problems in the body when it misfolds after secretion. While healthy ...

In 2020, news headlines repeated John Moult’s words at the end of a stunning competition: Artificial intelligence had “solved” a long-standing grand challenge in biology, protein structure ...

It has been a few years since AI began successfully tackling the challenge of predicting the three-dimensional structure of proteins, complex molecules that are essential for all life. Next-generation ...

Proteins, the pillars of cellular function, often assemble into 'complexes' to fulfill their functions. A study reveals why this assembly often begins during the very process of protein synthesis or ...

The protein was then synthesized and tested in the lab. It glowed—a clear sign of success. The AI had effectively charted a ...

It’s been trained on 771 billion unique tokens – the AI term for a unit of data – taken from databases of natural protein ...

In biology, the binding of cellular proteins to molecules called ligands produces myriad functions essential for life, including cell signaling and enzymatic action. In biotechnology and medicine, the ...

Insights into the structures could lead to improved treatment strategies for transthyretin amyloidosis, a progressive, fatal disease in men.

Ramakrishnan, a distinguished structural biologist and Nobel Laureate in Chemistry (2009), is renowned for his groundbreaking ...