and RNA stability, localization, structure and translation efficiency. Alternative polyadenylation (APA) generates mRNAs with varying 3′ termini. It is regulated by variation in the ...
Although subcellular RNA localization impacts gene expression through myriad ways, investigating localization simultaneously for many RNA species has been challenging. To address these obstacles, we ...
We use a variety of biochemical, biophysical, imaging, genomic and computational approaches to investigate the sequence-function relationship dictating RNA localization. The Fazal lab is growing! We ...
This is the localization of the ZSK-RNA in motor neurons whose shape was represented by tubulin, a structural protein. Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news ...
In protein transport, nuclear localization and nuclear export signals ... as does the export of 5S ribosomal RNA. The function of these multiple mRNA export factors is not yet certain.
I have established a strong and highly collaborative, extramurally funded research program examining the synthesis, transport and localization of various RNA species and its role in different cellular ...