Newcells' retinal models have been validated for screening and selecting the most effective adeno-associated viral (AAV) vectors with enhanced photoreceptor targeting for retinal gene therapy.

Two new compounds may be able to treat retinitis pigmentosa, a group of inherited eye diseases that cause blindness. The compounds, described in a study published January 14th in the open-access ...

The companies will work together by using the codon-optimized BBS1 AAV9 vector to minimize the vision loss caused by the ...

A collection of tests to evaluate cell viability, photoreceptor or RPE functionality and degeneration, and key marker expression and localization are examples of disease modeling packages.

Inherited retinal diseases (IRDs) are a group of monogenic disorders caused by mutations in more than 280 genes, and are characterized by progressive degeneration of photoreceptor cells in the retina.

A new study reveals the potential of two compounds in treating retinitis pigmentosa, a blinding genetic disorder. These compounds, identified through virtual screening, have shown promising results in ...

Using the stem cells, the researchers made "retinal sheets" that are enriched in immature versions of the cone photoreceptor cells, which could become mature cone cells when cultured in the lab.

Disruption of photoreceptor cilia has been implicated in a variety of retinal diseases, collectively called retinociliopathies, such as Leber congenital amaurosis and retinopathy of prematurity.