View Full Profile. Learn about our Editorial Policies. Alcohol is broken down in the human body by two main enzymes, alcohol dehydrogenase (ADH) and aldehyde dehydrogenase (ALDH). Mutations in these ...
Similarly, people with coding polymorphisms in aldehyde dehydrogenase 2 (ALDH2 ... these ‘lightweight genes’ tend to trigger reactions to alcohol, like nausea, thereby preventing overconsumption.