1983) which differed in their distribution, ligand binding and ... of a population of mu receptors, those that are allosterically coupled (in the complex); naloxone would not be able to recognize ...

and a DP2-Gi complex bound to indomethacin, a ligand known to favor β-arrestin signaling. These structures revealed distinct binding modes and provided critical insights into the receptor's ...

"These findings open new possibilities for protein-ligand complex modeling, indicating significant potential for ProteinReDiff in various biotechnological and pharmaceutical applications." ...

"These findings open new possibilities for protein-ligand complex modeling, indicating significant potential for ProteinReDiff in various biotechnological and pharmaceutical applications." ...

In biology, the binding of cellular proteins to molecules called ligands produces a myriad of functions essential for life, including cell signaling and enzymatic action. In biotechnology and medicine ...