is seriously affected when either of these kainate receptors is suppressed, both being necessary for synapse formation. Ana ...

Specifically, Teneurin-3 has been shown to cluster at presynaptic sites, promoting synapse formation through interactions with postsynaptic receptors like latrophilins. Interestingly, it appears ...

The three best examples of ion channel/receptor clustering in the nervous system are found at the synapse, the node of Ranvier, and the axon initial segment (AIS). In the case of the synapse, the ...

Other scientists have only recently identified hot and cold nerve cell receptors in the peripheral ... these neurons make a connection called a synapse that transmits cold sensory information ...

A study explores the molecular dynamics of CD28.ζ-CAR and 4-1BB.ζ-CAR T cells at the immune synapse, where CAR T cells bind to cancer cells. CD28.ζ-CAR T cells act like sprinters, killing cancer cells ...

such as the T cell receptor (TCR)–CD3 complex, from intracellular pools to the immune synapse. Finetti et al. observed that IFT20 (an IFT component that is essential for ciliary assembly ...

A study published in Science Advances shares new insights into how two of the most common types of chimeric antigen receptor (CAR ... dynamics at the immune synapse—where CAR T cells bind ...

Neurons have the amazing ability to self-organize into highly refined networks. I am interested in how these networks form. I am especially interested in the molecular pathways underlying this process ...

Investigating the molecular mechanisms underlying synapse unsilencing during development and its influence in Rett syndrome pathophysiology GluN2B-containing NMDA receptors regulate important ...

Seismic Therapeutic Inc. has provided preclinical data for S-4321, a novel dual-cell bidirectional (DcB) PD-1:FcγRIIb antibody being developed for the treatment of autoimmune disease.

These receive incoming impulses from other neurones. Receptor cells detect a change in the environment (a stimulus) and start electrical signals along neurons. These move towards the central ...